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Welcome to the TALC (Treatment of Advanced Laryngeal Cancer) study and thank you for your interest in our project.

The TALC study has been developed to improve the understanding and care of patients with laryngeal cancer. For many patients with cancer of the voice box, chemotherapy and radiation therapy frequently allow doctors to save voice boxes without sacrificing survival. However, we do not have full understanding of how these treatments affect a patient's quality of life, swallowing, and voice.

The goals of this study are to identify which factors lead to the best swallowing function after treatment and to document the impact of chemotherapy, radiation therapy, and surgery on swallowing, speech, and quality of life. With the help of doctors and patients, this project will allow researchers to increase successful treatment of laryngeal cancer.

Please contact us to learn more about the TALC study.


Enrolled subjects as of 04/02/2014:

Accrual to date 271
Mean age (years) 60.4
Gender 208 (76.8%) Male
62 (22.9%) Female
1 unknown
Treatment group 157 (57.9%) surgery
113 (41.7%) chemoradiation
1 unknown

Number of enrolled subjects over time:


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This study is sponsored by: